High-throughput screening (HTS) is a method used in drug discovery and other scientific fields to quickly and efficiently test large numbers of compounds for a specific biological activity. This process involves the automated testing of thousands to millions of candidate molecules or genetic materials for their ability to interact with a target biomolecule or cellular pathway. HTS allows researchers to rapidly identify potential drug candidates, study enzyme function, or investigate biological processes on a large scale. It typically involves the use of robotic systems to prepare and test samples, as well as advanced data analysis techniques to analyze the results. Overall, high-throughput screening is a valuable tool for accelerating the process of drug discovery and advancing our understanding of complex biological systems.